The psycho criminal from both is named Tuco.
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Welcome @harrypyeeter and good catch…I didn’t put two and two together!
On a loose tangential path Bryan Cranston’s first screen credit was for the English dub of the animated ‘Call of the Wild: Howl, Buck’ (Japanese original title Arano no Sakebi Koe: Hoero, Buck), an animated TV movie from 1981.
It was based on the Jack London book that was the companion piece to his ‘White Fang’ , filmed as ‘Zanna Bianca’ in 1973 and starring Franco Nero.
I did say loose. 
Great show but I don’t personally see too many similiarities to SWs
I see some similarities, such as what harrypyeeter mentioned, the major Mexican character being named 'Tuco.
Also, of course, the whole Western aesthetic; the music, desert setting, the imagery, the criminal standoffs, all of which, definitely at times, seem to veer into Spaghetti-flavored territory.
Something else is the paternal mentor/pupil relationship between the older veteran master, Walt, with the young protege, Jesse, which, of course, is kind of a subgenre unto itself within Spaghetti Westerns, exemplified with a fistful of Lee Van Cleef movies, such as “For a Few Dollars More”, “Death Rides a Horse”, “Day of Anger”, “the Grand Duel”, among others in this category.
Another thing, an admittedly huge thing that I don’t think anyone has mentioned is: The sudden explosive machine gun massacre climax.
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